Family History and Prognosis of Prostate Cancer

F Jansson - 2020 - search.proquest.com
… • Two or more relatives with early onset prostate cancer, ie … G84E and association to
significant prostate cancer is … pathology after prostatectomy is not known. We aim to evaluate if …

Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer

MR Trendowski, C Sample, T Baird… - JCO Precision …, 2022 - ascopubs.org
early-onset prostate cancer and/or a positive family history of … Its association with age at
onset and advanced disease in … of relevant clinical data but also histopathologic confirmation of …

A prospective study of birth weight and prostate cancer risk and mortality in the Health Professionals Follow-up Study

Q Liu, Y Zhang, JB Vaselkiv, LA Mucci… - … Journal of Cancer, 2024 - nature.com
… analyses for early-onset prostate cancer (diagnosis before 65 … the association between birth
weight and prostate cancer risk … Diagnoses were confirmed by medical record and pathology

[HTML][HTML] Polygenic risk score for genetic evaluation of prostate cancer risk in Asian populations: A narrative review

SH Song, SS Byun - Investigative and clinical urology, 2021 - ncbi.nlm.nih.gov
… to early onset and aggressive disease [26,27], PCa, like most … (SNP) with positive or negative
associations are becoming … and aggressive PCa pathology compared to Caucasian and …

Evaluating germline testing panels in southern African males with advanced prostate cancer

K Gheybi, J Jiang, SBA Mutambirwa, PXY Soh… - … Comprehensive Cancer …, 2023 - jnccn.org
… advanced, early-onset, and familial prostate cancer genetic … of 441 patients with known
pathology), respectively. Although the … Medical Research Council and the Cancer Association of …

Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - … Reviews Clinical …, 2022 - nature.com
… Data from another study indicate a positive association between birthweight and colon cancer
risk in adulthood 30 . Exposure to ionizing radiation and age at menarche are other factors …

Germline pathogenic variants in patients with early-onset neuroendocrine neoplasms

RP Riechelmann, MDS Donadio… - … -Related Cancer, 2023 - erc.bioscientifica.com
… the association of a GPV with the biology of a given cancer, … of histological diagnosis of
several family members with, … have a positive family history of any cancer and family history of …

Genetic predisposition to prostate cancer: an update

H Ni Raghallaigh, R Eeles - Familial Cancer, 2022 - Springer
… -wide association studies have led to … early onset of the disease and men with inherited
germline variants in DNA repair genes are particularly at risk for harbouring aggressive histology. …

[HTML][HTML] Identifying proteomic risk factors for overall, aggressive and early onset prostate cancer using Mendelian randomization and tumor spatial transcriptomics

TA Desai, ÅK Hedman, M Dimitriou, M Koprulu, S Figiel… - medRxiv, 2023 - ncbi.nlm.nih.gov
… , African ancestry, family history of the disease, circulating … between benign and GG4 prostate
histology (Gleason Score = 8)… protective association we observe with prostate cancer risk is …

Clinical implications of germline testing in newly diagnosed prostate cancer

S Loeb, VN Giri - European urology oncology, 2021 - Elsevier
… is intraductal pathology or if the family history is suspicious. … at the European Society for
Medical Oncology 2019 meeting … a higher risk of PCa and early-onset disease, as supported by …